First edition in English. 8vo. Pp. [viii], 68. Black cloth, lettered in white to spine. The scarcer casebound issue. Originally published as Syndrom mizející plíce by Mladá fronta, Prague.
A poetry collection organized around a series of medical metaphors, with sections entitled "Syncope," "Syndrome," "Symptom," and "Synapse." Some poems, including "Heart Transplant" and the title poem, first published in periodicals, such as American Poetry Review, FIELD, New England Review / Bread Loaf Quarterly, and Ploughshares, hew closely to this scheme, while others range more widely.
A rare mediator between scientific and literary modes of discourse – unsurprising for someone who was a scientist by vocation and considered poetry a pastime. "Holub is an immunologist, and the rigorous logic of the scientist shows in many of the poems, which are almost mathematical in their analogies. But it is a mathematics with blood in it." –Paul Breslin, Poetry